David Mester

Symic Bio, Inc. develops new category of therapeutics. The company studies treatments for osteoarthritis and cardiovascular ailments. The firm developed a new therapeutic category of bioconjugates that directly target the extracellular matrix, the biologically active environment which plays critical roles for cell proliferation, migration, differentiation and survival. The company was founded by Kate Stuart and John Paderi in 2012 and is headquartered in San Francisco, CA.

Impact Vitals. develops machine learning software for data analysis. It focuses on developing its Cipher Sensor technology to address unmet needs in several medical fields where clinical decision making is often compromised due to ineffective processing of large volumes of data during the diagnosis and treatment process. The company was founded by Greg Grudic and Steven Moulton in 2009 and is headquartered in Boulder, CO.

Harpoon Medical, Inc. develops surgical services. It offers an image-guided, minimally invasive surgical tool for mitral valve repair that enables surgeons to access and repair the mitral valve in a beating heart via a small incision between the ribs without the need for cardiac arrest or cardiopulmonary bypass. The company was founded by James S. Gammie and Peter Wilson in July 2013 and is headquartered in Baltimore, MD.

Toucan Capital Corp (Toucan Capital) is a private equity firm founded in 1997 by Linda F. Powers and Robert F. Hemphill. The firm is headquartered in Bethesda, Maryland.

Duke University is an academic university that offers undergraduate, graduate and professional programs. It also has publications and research services. The university was founded in 1838 and is headquartered in Durham, NC.

University of Southern California is a private research university that mainly offers undergraduate, graduate & other higher education. The university was founded in 1880 and is headquartered in Los Angeles, CA.

Epidarex Capital Partners LLC (Epidarex Capital) is a venture capital firm founded in 2010 by Kyparissia Sirinakisvin. The firm is headquartered in Bethesda, Maryland.

Ajax Health LLC (Ajax Health) is a private Equity and venture capital firm founded in 2017 by Duke S. Rohlen. The firm is headquartered in Menlo Park, California.

Raydiant Oximetry, Inc. engages in the development of biomedical devices to monitor the oxygen levels in fetal blood. The company was founded in 2016 and is headquartered om Mountain View, CA.

Ablacon, Inc. provides machine learning based electrographic mapping services for heart treatments. The company was founded by Peter Ruppersberg in 2015 and is headquartered in Wheat Ridge, CO.

EPMap-System GmbH & Co. KG manufactures medical apparatus and materials. It is a integrated solution for recording, stimulation, navigation and aplation of the Heart. The company was founded by Manfred Piechura and is headquartered in Herdecke, Germany.

Verix Health, Inc. engages in the development of surgical needle for invasive treatment of cancer tumors. The company was founded by Mark Yim and is headquartered in Philadelphia, PA.

Serpex Medical, Inc. provides biomedical services. The company is headquartered in Santa Clara, CA.

Sonnest, Inc. is a company that specializes in developing a contrast agent called Electrast™. The company is based in Baltimore, MD. The inspiration for Electrast™ began in 2015 through a collaboration between Dr. Wrenn, the company's Chief Scientific Officer, and Dr. Brett Angel, an electrophysiologist at Drexel University. Electrast™ is a voltage-activated ultrasound contrast agent that activates with ultrasound and the heart's local electric field if the heart tissue is perfused and viable. The company was founded in 2019 by Steve Wrenn, Brett Angel. The CEO is Peter Boyd.

RapidPulse, Inc. is a medical device company that specializes in developing minimally invasive vascular products for ischemic stroke. The company is based in Miami, FL. The company is focused on advancing the development of the RapidPulse™ cyclic aspiration system, which includes a novel aspiration pump to allow rapid and consistent removal of blood clots from the brain. RapidPulse is a spinout of Syntheon LLC, a medical device incubator dedicated to developing innovative products in the medical device industry. The CEO of the company is Sean McBrayer.

The American company is focused on developing the Carlen technology, a transcatheter technology for the treatment of mitral regurgitation. The technology preserves the physiological valve geometry while restoring its function, eliminates the risk of stenosis, and offers the benefit of preserving a full range of transcatheter and surgical treatments as future options. Nyra Medical is also developing a novel transcatheter mitral and tricuspid valve repair technology called the Cardiac Leaflet Enhancer (Carlen), which enables repair of leaky heart valves without the need for open heart surgery. Lori B. Chmura has been the CEO of the company since 2023.