Sergejs Jakimovs

Part of InSilico Medicine Hong Kong Ltd., InSilico Medicine, Inc. is a clinical stage biotechnology company based in New York, NY. InSilico Medicine is focused on generative models, reinforcement learning, and other modern machine learning techniques for the generation of new molecular structures with specified parameters, generation of synthetic biological data, target identification, and prediction of clinical trials outcomes. The company has developed AI platforms that utilize deep generative models, reinforcement learning, transformers, and other modern machine learning techniques for novel target discovery and the generation of novel molecular structures with desired properties. InSilico Medicine is developing breakthrough solutions to discover and develop innovative drugs for cancer, fibrosis, immunity, central nervous system diseases, infectious diseases, autoimmune diseases, and aging-related diseases. The company was founded in 2014 by Aleksandr Aliper and Aleksandrs Zhavoronkov. Aleksandrs Zhavoronkov has been the CEO since 2014.

SIA Longenesis promotes collaboration between biomedical institutions, patient organizations, and research partners. The company is based in Riga, Latvia and has subsidiaries in Hong Kong. The Latvian company identifies biomedical data from metadata files, onboards population cohorts, and engages new patients in research. The company was founded by Garri Zmudze.

Deep Longevity Ltd. develops artificial intelligence systems to track the rate of aging at the molecular, cellular, tissue, organ, system and psychological levels. Its products include longevity cloud, recommendation engines, deep aging clocks and age metric reports. The company was founded in 2020 by Alex Zhavoronkov and is headquartered in San Diego, CA.

Colby is transitioning to a clinical stage drug development company. The company was launched as a Wisconsin Alumni Research Foundation (WARF) spin-out and is strategically aligned with leading clinicians and drug discovery scientists at the University of Wisconsin Paul P. Carbone Comprehensive Cancer Center (UWCCC). Colby is accessing data from funded grants and private investment to develop its therapeutic drugs for therapy-resistant and hypoxic conditions. Colby's lead drugs have unique mechanisms of action and target specific pathways. The company is focused on clinical development of its lead drugs, CPC-100 and -200, in patients with recurrent PCa and other solid tumors, respectively. In 2010, Colby plans to launch a Phase I/IIa study of CPC-100 in men with PCa who fail Androgen Depletion Therapy, as evidenced by rising PSA levels. CPC-200 is being scheduled for a Phase I/IIa in men with high-risk tumors. Colby's two pipeline drugs, CPC-300 and CPC-410 for therapy-resistant metastatic and hypoxic tumors are in late pre-clinical development and are funded by federal grants, including an awarded Colby SBIR grant and by private investors. The Company has demonstrated safety of its lead drugs following efficacy studies in rodents and toxicology studies in mice, rats, and dogs.

Orisdx, Inc. provides a saliva-based molecular detection method to check oral cavity pre-malignancies and cancers. The private company is based in Chicago, IL. The company was founded by Evgeny G Izumchenko.

Y-Trap, Inc. develops novel immunotherapy for cancer. The private company is located in the US. The American company was founded by Evgeny G Izumchenko.

Repair Biotechnologies, Inc. operates as a biotechnology company which develops clinic therapies. It specializes in developing reversing atherosclerosis and atrophy of the thymus. The company was founded by Reason Cherman and Bill Cherman in 2018 and is headquartered in Syracuse, NY.

Human Longevity, Inc. provides precision health analytics to individuals through the Health Nucleus. The Health Nucleus is an assessment of current and future risk for cardiac, oncologic, metabolic and cognitive diseases and conditions. The firm offers database of sequenced genomes and phenotypic data. The company was founded by J. Craig Venter, Robert Joseph Hariri Gordon, and Peter H. Diamandis in 2013 and is headquartered in San Diego, CA.

Holmusk USA, Inc. develops predictive algorithms that offer insights for personalized care and population health management. It focuses on solving problems in healthcare for chronic diseases. The firm's products include AptCare Suite, which is a digital health management platform built for community chronic care, and MindLinc, which integrates mental and behavioural health and practice management at all levels. The company was founded by Nawal Roy in 2015 and is headquartered in Singapore.

Welltech Ventures is a venture capital firm founded in 2019 by Galit Horovitz and Amir Alroy. The firm is headquartered in Tel Aviv, Israel.

Pretiosum Ventures Services Ltd (Pretiosum Ventures) is a venture capital firm founded in 2019 by Yana Abranova. The firm is headquartered in London, United kingdom.

Axia Ventures Group Ltd. (Broker) (AXIA Greece) is the Greece-based securities brokerage branch of Axia Ventures Group Ltd. (ATHEX: EX) in Cyprus. Headquartered in Athens, AXIA Greece provides capital market-related services to corporates, governments and institutional clients.

Bacmuno Biotechnology Ltd. provides bacteria-based immunotherapies against cancer. It applies Salmonella genetic modification technology to cancer immunotherapy in animals and humans. The company was founded on January 23, 2017 and is headquartered in Hong Kong.

Cellomics International Ltd. is a Chinese biotechnology company that focuses on developing and commercializing liquid biopsy products and services. The company is based in Hong Kong, Hong Kong. Cellomics International was founded by Christine Huang and Edwin Yu, with Christine Huang serving as the CEO since incorporation.

Queen Mary Hospital operates general medical hospitals. The private company is based in Hong Kong, Hong Kong. The CEO of the Chinese company is Yau Fun Lau.

Pantelakis Securities SA provides brokerage services. The private company is based in Athens, Greece. The Greek company was founded in 1920. The CEO is Nikos Pantelakis.

Uni.Fund invests in start-up companies located in Greece. The fund invests in sectors such as technology services, electronic technology, health services, health technology, finance and insurance technology. It provides equity financing for pre-seed, seed and early stage capital requirements. It makes investments in pre-seed up to EUR 250,000 while EUR 250,000 - 500,000 in seed stage.

CellPly SRL develops and markets customized diagnostic tools for cancer treatment. The firm specializes in the design and marketing of solutions for defining the efficacy of immunotherapies and chemotherapies on cancer and immune cells. It offers a platform that analyzes ex-vivo samples and rare cells immediately after obtaining them from patients and preserving microenvironment conditions to readily provide information about tumor cell sensitivity to drugs and in-vivo status of single immune cells located close to tumor cells. The firm focuses on helping oncologists selecting the best treatment options, scientists studying cell response to therapy, and pharmaceutical companies increasing drug efficacy and rescuing drugs with limited efficacy through patient stratification. The company was founded by Massimo Bocchi and Roberto Guerrieri in 2013 and is headquartered in Bologna, Italy.

F. Hoffmann-La Roche Ltd. manufactures pharmaceutical products. It offers pharmaceutical drugs, pharmaceutical instruments, and diagnostics solutions. The company was founded by Fritz Hoffmann-La Roche on October 1, 1896 and is headquartered in Basel, Switzerland.

The Alliance for Artificial Intelligence in Healthcare (AAIH) is an advocacy organization that aims to improve patient outcomes and minimize healthcare costs through the discovery, development, and delivery of better solutions. The private company is based in Long Island City, NY, and was founded by Brandon Allgood. The organization fosters creativity, collaboration, and knowledge sharing among its members, who come from diverse backgrounds in science, math, technology, and healthcare. AAIH is focusing on two primary practice areas in 2023: developing a comprehensive framework for digitizing IND and addressing core challenges in data accessibility through a real-world data registry.

Koatum SIA provides implantable products of medical engineering, such as dental, orthopedic and reconstructive implants. The company was founded in 2014 and is headquartered in Jurmala, Latvia.

Vortex Oil Engineering SIA produces and maintains the devices for increasing oil recovery from productive oil layers. Its technology is used in water flooding process. The company was founded by Sergey Jakimov and is headquartered in Riga, Latvia.

Rietumu Banka AS provides commercial banking services. It offers recurring transfers, mortgages, subordinated bonds, term deposits, fixed income funds, leasing, letter of credit, charge cards and insurance services. The firm also remote banking, corporate consulting and same-day payments services. The company was founded by Arkady Suharenko and Leonid Esterkin on May 13, 1992 and is headquartered in Riga, Latvia.

InSilico Medicine Cayman TopCo is a holding company, which engages in the research and development of generative artificial intelligence (AI) driven therapeutic pipeline and software licensing. Its pipeline targets areas include high unmet needs, with a footprint in fibrosis, oncology, immunology, and other therapeutic areas. The company was founded by Alex Zhavoronkov on November 19, 2018 and is headquartered in Hong Kong.

Insilico Medicine IP Ltd. engages in the investment of drug discovery and drug development through the deployment of new artificial intelligence technologies. The company was founded on June 21, 2019 and is headquartered in Hong Kong.